Take tram line 3, S1/11, S5, S2, 1, 4, 5, S4/41 or 2 to the stop "Marktplatz". From there, go along Kaiserstraße towards Europaplatz. The KERN branch is opposite the department store chain "Karstadt" and next to the shoe shop "Deichmann".
If you're coming from the main railway station, take tram line S1/11 (towards Hochstetten), S4/41 (towards Heilbronn) or 2 (towards Wolfartsweier) and get off at the stop "Marktplatz".
The car park exit leads onto Zähringerstraße. Turn right there then turn left onto Lammstraße. Follow the road and then turn left onto Kaiserstraße and you will reach 84 Kaiserstraße.